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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
TCTP_HUMAN
USC-OGP 2-DE database
:
TCTP_HUMAN
TCTP_HUMAN
General information about the entry
View entry in simple text format
Entry name
TCTP_HUMAN
Primary accession number
P13693
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Translationally-controlled tumor protein; Short=TCTP; AltName: Full=Fortilin; AltName: Full=Histamine-releasing factor; Short=HRF; AltName: Full=p23;.
Gene name
Name=TPT1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-5
{PLATELET 4-5}
Homo sapiens (Human)
map experimental info
PLATELET_4-5
MAP LOCATIONS:
SPOT OGP-0209
:
pI=4.72; Mw=23079
SPOT OGP-0210
:
pI=4.80; Mw=22897
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1299
:
pI=4.88; Mw=23684
SPOT OGP-1300
:
pI=5.70; Mw=23333
Cross-references
UniProtKB/Swiss-Prot
P13693; TCTP_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
TCTP_HUMAN
Primary accession number
P13693
Secondary accession number(s)
B2R7E5 Q6YLS2 Q7Z4J4 Q8TBK7 Q96EE2 Q9UC70
Sequence was last modified on
January 1, 1990 (version 1)
Annotations were last modified on
March 15, 2017 (version 185)
Name and origin of the protein
Description
RecName: Full=Translationally-controlled tumor protein; Short=TCTP; AltName: Full=Fortilin; AltName: Full=Histamine-releasing factor; Short=HRF; AltName: Full=p23;
Gene name
Name=TPT1
Encoded on
Name=TPT1
Keywords
3D-structure
;
Alternative splicing
;
Calcium
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X16064; CAA34200.1
; -; mRNA
EMBL
AJ400717; CAB87812.1
; -; Genomic_DNA
EMBL
AY334563; AAQ01550.1
; -; mRNA
EMBL
AY117678; AAM51565.1
; -; mRNA
EMBL
CR457036; CAG33317.1
; -; mRNA
EMBL
AK312951; BAG35792.1
; -; mRNA
EMBL
AL138963; CAH72034.1
; -; Genomic_DNA
EMBL
CH471075; EAX08731.1
; -; Genomic_DNA
EMBL
CH471075; EAX08732.1
; -; Genomic_DNA
EMBL
BC003352; AAH03352.1
; -; mRNA
EMBL
BC012431; AAH12431.1
; -; mRNA
EMBL
BC022436; AAH22436.1
; -; mRNA
EMBL
BC052333; AAH52333.1
; -; mRNA
CCDS
CCDS66538.1; -. [P13693-2]
; .
CCDS
CCDS9397.1; -. [P13693-1]
; .
PIR
S06590; S06590
; .
RefSeq
NP_001273202.1; NM_001286273.1. [P13693-2]
; .
RefSeq
NP_003286.1; NM_003295.3. [P13693-1]
; .
UniGene
Hs.374596; -
; .
UniGene
Hs.717316; -
; .
PDB
1YZ1; X-ray
; 2.00 A; A/B/C/D=1-172
PDB
2HR9; NMR
; -; A=1-172
PDB
3EBM; X-ray
; 2.60 A; A/B/C/D=1-172
PDB
4Z9V; X-ray
; 2.10 A; C/D/E/F/G/H=11-31
PDBsum
1YZ1; -
; .
PDBsum
2HR9; -
; .
PDBsum
3EBM; -
; .
PDBsum
4Z9V; -
; .
ProteinModelPortal
P13693; -
; .
SMR
P13693; -
; .
BioGrid
113030; 32
; .
DIP
DIP-40097N; -
; .
IntAct
P13693; 32
; .
MINT
MINT-2634453; -
; .
STRING
9606.ENSP00000431872; -
; .
Allergome
3816; Hom s TCTP
; .
iPTMnet
P13693; -
; .
PhosphoSitePlus
P13693; -
; .
SwissPalm
P13693; -
; .
DMDM
136479; -
; .
DOSAC-COBS-2DPAGE
P13693; -
; .
OGP
P13693; -
; .
REPRODUCTION-2DPAGE
IPI00550900; -
; .
SWISS-2DPAGE
P13693; -
; .
EPD
P13693; -
; .
MaxQB
P13693; -
; .
PaxDb
P13693; -
; .
PeptideAtlas
P13693; -
; .
PRIDE
P13693; -
; .
TopDownProteomics
P13693-1; -. [P13693-1]
; .
DNASU
7178; -
; .
Ensembl
ENST00000379055; ENSP00000368344
; ENSG00000133112. [P13693-2]; .
Ensembl
ENST00000379056; ENSP00000368345
; ENSG00000133112. [P13693-2]; .
Ensembl
ENST00000530705; ENSP00000431872
; ENSG00000133112. [P13693-1]; .
GeneID
7178; -
; .
KEGG
hsa:7178; -
; .
UCSC
uc001uzy.3; human. [P13693-1]
; .
CTD
7178; -
; .
DisGeNET
7178; -
; .
GeneCards
TPT1; -
; .
HGNC
HGNC:12022; TPT1
; .
HPA
CAB008364; -
; .
HPA
HPA039437; -
; .
MIM
600763; gene
; .
neXtProt
NX_P13693; -
; .
OpenTargets
ENSG00000133112; -
; .
PharmGKB
PA36701; -
; .
eggNOG
KOG1727; Eukaryota
; .
eggNOG
ENOG4111FVP; LUCA
; .
GeneTree
ENSGT00390000006051; -
; .
HOGENOM
HOG000203361; -
; .
HOVERGEN
HBG002282; -
; .
InParanoid
P13693; -
; .
PhylomeDB
P13693; -
; .
TreeFam
TF300238; -
; .
SIGNOR
P13693; -
; .
ChiTaRS
TPT1; human
; .
EvolutionaryTrace
P13693; -
; .
GeneWiki
TPT1; -
; .
GeneWiki
Translationally-controlled_tumor_protein; -
; .
GenomeRNAi
7178; -
; .
PRO
PR:P13693; -
; .
Proteomes
UP000005640; Chromosome 13
; .
Bgee
ENSG00000133112; -
; .
CleanEx
HS_TPT1; -
; .
ExpressionAtlas
P13693; baseline and differential
; .
Genevisible
P13693; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005615; C:extracellular space
; IDA:MGI; .
GO
GO:0005771; C:multivesicular body
; IDA:MGI; .
GO
GO:0005634; C:nucleus
; IDA:MGI; .
GO
GO:0005509; F:calcium ion binding
; IDA:UniProtKB; .
GO
GO:0008017; F:microtubule binding
; IBA:GO_Central; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0006816; P:calcium ion transport
; IC:UniProtKB; .
GO
GO:0030154; P:cell differentiation
; IBA:GO_Central; .
GO
GO:0006874; P:cellular calcium ion homeostasis
; IC:UniProtKB; .
GO
GO:0043066; P:negative regulation of apoptotic process
; TAS:UniProtKB; .
GO
GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
; IMP:MGI; .
GO
GO:0042981; P:regulation of apoptotic process
; NAS:UniProtKB; .
GO
GO:0009615; P:response to virus
; IEP:UniProtKB; .
Gene3D
2.170.150.10; -
; 1; .
InterPro
IPR011057; Mss4-like
; .
InterPro
IPR011323; Mss4/transl-control_tumor
; .
InterPro
IPR018103; Translation_control_tumour_CS
; .
InterPro
IPR018105; Translational_control_tumour_p
; .
PANTHER
PTHR11991; PTHR11991
; 1; .
Pfam
PF00838; TCTP
; 1; .
PRINTS
PR01653; TCTPROTEIN
; .
SUPFAM
SSF51316; SSF51316
; 1; .
PROSITE
PS01002; TCTP_1
; 1; .
PROSITE
PS01003; TCTP_2
; 1; .
PROSITE
PS51797; TCTP_3
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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